Situated in the heart of the historic city center of Istanbul, Avicenna Hotel is within walking distance from Hagia Sophia ,Blue Mosque and Topkapi Palace. The Ataturk International Airport is located roughly 15 kilometers from the Avicenna Hotel. The proximity to the historic district eliminates the necessity of transportation back and forth between it and the hotel itself.

The Avicenna Hotel features a design scheme that combines traditional Ottoman elements with modern sensibilities and this carries over into the rooms. The rooms are provided with air conditioning, minibars, safes, televisions and are designed to offer a cozy atmosphere.

The Avicenna Hotel was originally a traditional wooden house, dating to the 19th Century, which was converted to use as a hotel in 1990. It was fully-renovated in 2008 and is now a luxury facility and one of the Istanbul hotels located near the city's most historic districts.